Physiological Changes in Pregnancy
·
During pregnancy
there are progress anatomical and physiological changes.
·
These changes do
not only occur at the genital organs but also to all the system of the body.
·
This is due to
increasing demands of the growing fetus.
I. Changes in genital organs
1. Vulva
·
It becomes edematous and hyperemic.
·
The labia minora become pigmented and
hypertrophied
2. Vagina
·
It becomes
hypertrophied vascular and edematous
·
The vaginal
secretions becomes copious, thin and curly white
·
The ph becomes
more acidic.
3. Uterus
·
There is increase
in size of uterus
·
It measures 35
cms in length and 900-1000 gms
·
Changes occur in
all the parts of uterus.
·
The uterine
muscles undergo hypertrophied and hyperplasia.
·
The fondues
enlarged more than the body if the uterus.
·
The 3 distinct
layers of uterus muscles can be made out.
·
In a turn the
uterus differentiates into an active upper segment which is more muscular and a
passive lower segment which is least muscular.
·
The cervix is
deviated to the left side (levo-rotation), bringing it closer to the ureter due
to lateral obliquity.
II. Breast
·
There is increase
in the size of the breast due to hypertrophy and proliferation of the ducts
alveoli.
·
The vascularity
increase which result in the appearance of bluish veins running under the skin.
·
The nipples
becomes larger, erectile and are deeply pigmented
·
The sebaceous
glands which remains invisible in the non-pregnant state becomes hypertrophied
over the areola during pregnancy and are called as Montgomery‘s tubercles
·
Secondary areola
is seen in the 2nd trimester
·
Secretions may
also been seen at about 12 weeks of pregnancy
·
Breast weight is
increased approximately to 500-800 gm
III. Endocrine system
·
Changes are
brought about by progesterone, estrogen and relaxin hormones
a. Effects of progesterone
·
Reduction in tone of smooth muscles resulting
in nausea, reduced peristalsis, constipation, bladder toned is decreased,
dilation of veins and decreased diastolic pressure
·
Increase in body temperature
·
Increased storage of fats
·
Development of breast, alveolar and glandular
milk producing cells
b. Effects of estrogen
·
Increased growth of uterus and breast ducts
·
Increased levels of prolactin for lactation
·
Maternal calcium metabolism
·
Higher levels may result in increased vaginal
glycogen resulting in “thrush”.
c. Effects of relaxin
·
Replacement of collage in pelvic joints, capsules,
cervix, resulting in greater extensibility and pliability
·
Inhibition of myometrial activity
·
Helps in distension of uterus and provides
additional supporting connective tissues.
·
Has a role in cervix ripening
IV. Cutaneous changes
·
There is
formation of chlosma gravidarum or pregnancy mark in the form of pigmentation
around the cheek which is patchy or diffused and it disappears after delivery
·
It also shows
formation of linea nigra which is a brownish black pigmentation in the midline
of the abdomen stretching from the xiphisternum to the pubic symphysis. It
usually disappears after delivery.
·
Striae gravidarum
are slightly depressed linear marks with varying length and breath. These are
seen just below the umbilicus
·
These are pinkish
during delivery which becomes glistening white after pregnancy and is then
called as striae albicans
V. Weight gain
·
A pregnant lady
puts on about 10-12 kg of weight
·
In early
pregnancy the lady may loose weight due to nausea and vomiting but later the
weight gain is progressively increased to about 2 kg every month
VI. CVS changes
·
Increase in blood
volume by 40%
·
Increase in
plasma level than red cells and Hb level falls by 80%. This is called as
dilution anemia or physiological anemia due to pregnancy
·
During 3rd trimester,
the weight of fetus may compress the aorta and IVC against the lumbar spine in
lying position causing dizziness, unconsciousness and is called as pregnancy
hypotensive syndrome.
·
Increase in
cardiac output by 40%
·
Stroke volume
increased by 30%
·
Heart rate
increased by 30%
·
Heart rate
increased by 15 beats/min
VII. Respiratory system
·
Respiratory rate
increases from 15-18 breath/min (hyperventilation)
·
Alveolar
ventilation increases
·
Tidal volume
increases up to 40%
·
Diaphragm is
raised by 40 mm
·
Chest diameter is
increased by 20 mm
·
CO2
tension is decreased
·
PaO2 –
92 mm of Hg
·
PaCO2
– 30 mm of Hg
VIII. GIT and urinary system
·
respiratory rate
increases from 15 to 18 breath/min(Hyperventilation)
·
Alveolar
ventilation increases.
·
Tidal volume
increases up to 40%
·
Diaphragm is
raised up to 40mm
·
Chest diameter is
increased by 2mm
·
CO2
tension is decreased
·
PaO2—92mm
of Hg
·
PaCo2
__ 30mm of Hg
VIII. GIT and Urinary
system:
·
Nausea and
vomiting due to response by human chronic Gonadotrophin (HCG)
·
Delayed gastric
emptying and thus shows constipation
·
Increased
concentration of bile in gall bladder
·
There is
increased in the size and weight of kidney and dilation of the renal pelvis
·
Dilation of
uterus causes pooling and stagnation of urine resulting in U.T.I.
IX. Musculoskeletal system
·
Increased joint
laxity
·
Increased lumbar
lordosis due it change in COG and pelvic tilting
·
The distance
between the two rectus abdominal muscles widens and the linea alba may split
under the strain called as Diastasis Recti
·
Edema of ankle
due to water retention
·
Compression of
nerves causing carpel tunnel syndrome
X. Psychological and emotional changes
·
Mood swings
·
Depression
·
Anxiety